Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/337112
Type: Artigo
Title: The relationship between quality of life, cognition, and thyroid status in graves' disease
Author: Riguetto, Cinthia Minatel
Neto, Arnaldo Moura
Tambascia, Marcos Antonio
Zantut-Wittmann, Denise Engelbrecht
Abstract: PurposeTo assess quality of life (QoL) and cognitive function among Graves' disease (GD) patients with different thyroid status, with and without ophthalmopathy.MethodsThis is a cross-sectional clinic-based study involving 154 patients with GD (81.27% were female, mean age 45.6SD 11.2 years) and 54 (35.06%) had ophthalmopathy. Data were collected after an informed consent from all patients was obtained. All patients completed the 36-Item Short Form Health Survey and Mini-Mental State Examination. Patients with ophthalmopathy also completed the Graves' Orbitopathy Quality of Life Questionnaire.ResultsPatients with hyperthyroidism presented a greater impairment in QoL when compared to euthyroidism group. A lower score in physical role functioning was found in both subgroups with active disease (hyperthyroidism and euthyroidism using thionamides). A lower score was also seen in visual function, only in patients with hyperthyroidism, without difference in appearance. No difference was found in cognition between patients. Younger ages at diagnosis, male sex, euthyroidism and absence of ophthalmopathy were factors associated with better QoL, as well as a shorter disease duration was associated with better recall, attention and calculation.Conclusions An impairment in QoL among patients with active GD was evidenced, even in those receiving thionamides and in euthyroidism. Ophthalmopathy was a factor associated with a poor QoL and no clear evidence of cognitive impairment was demonstrated
Subject: Hipertireoidismo
Oftalmopatia de graves
Doença de graves
Country: Alemanha
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/s12020-018-1733-y
Address: https://link.springer.com/article/10.1007/s12020-018-1733-y
Date Issue: 2019
Appears in Collections:FCM - Artigos e Outros Documentos

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