Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/329340
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt
dc.contributor.authoremailhumbertomilagre@iq.unesp.brpt
dc.typeArtigopt
dc.titleMaldi Imaging Mass Spectrometry Of Fresh Water Cyanobacteria: Spatial Distribution Of Toxins And Other Metabolitesen
dc.contributor.authorSandonato
dc.contributor.authorBeatriz B.; Santos
dc.contributor.authorVanessa G.; Luizete
dc.contributor.authorMilena F.; Bronzel
dc.contributor.authorJoao L.
dc.contributor.authorJr.; Eberlin
dc.contributor.authorMarcos N.; Milagre
dc.contributor.authorHumberto M. S.
unicamp.authorEberlin, Marcos N.] Univ Estadual Campinas, Univ Estadual Campinas, Inst Quim, Lab Thomson Espectrometria Massas, BR-13084971 Campinas, SP, Brazilpt_BR
unicamp.author.external[Sandonato, Beatriz B.pt_BR
unicamp.author.externalLuizete, Milena F.pt_BR
unicamp.author.externalBronzel, Joao L., Jr.pt_BR
unicamp.author.externalMilagre, Humberto M. S.] UNESP, Univ Estadual Paulista Julio Mesquita Filho, Inst Quim, BR-14800060 Araraquara, SP, Brazilpt_BR
unicamp.author.external[Santos, Vanessa G.pt_BR
dc.subjectCyanobacteriaen
dc.subjectMaldi-tofen
dc.subjectMass Spectrometryen
dc.subjectImagingen
dc.description.abstractCyanobacteria are among the most ancient forms of life, yet they are known to synthesize highly sophisticated defense molecules, such as the highly hepatotoxic cyclic peptides microcystins and nodularins produced by the genera Microcystis, Anabaena and Nodularia. These metabolites are released by cyanobacteria to water environments causing episodes of fatalities among animals and humans. To better understand the releasing of these metabolites, imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) was herein applied to determine the spatial distribution of such toxins directly on agar-based cultures. Other key metabolites such as aeruginosin 602 and the siderophore anachelin were also mapped in mixed cyanobacterial cultures, showing the great potential of IMS to spatially monitor the biochemical details of cyanobacterial defense and interactions.en
dc.relation.ispartofJournal of the Brazilian Chemical Societypt
dc.publisherSoc Brasileira Quimicaen
dc.publisherSão Pauloen
dc.date.issued2017pt
dc.date.monthofcirculationabrpt
dc.identifier.citationJournal Of The Brazilian Chemical Society. Soc Brasileira Quimica, v. 28, p. 521 - 528, 2017.
dc.language.isoEnglishpt
dc.description.volume28pt
dc.description.issuenumber4pt
dc.description.initialpage521pt
dc.description.lastpage528pt
dc.rightsabertopt
dc.sourceWOSpt
dc.identifier.issn0103-5053pt
dc.identifier.eissn1678-4790pt
dc.identifier.wosidWOS:000396347700001pt
dc.identifier.doi10.5935/0103-5053.20160191pt
dc.identifier.urlhttp://www.scielo.br/scielo.php?pid=S0103-50532017000400521&script=sci_arttextpt
dc.description.sponsorshipBrazilian research foundation FAPESP
dc.description.sponsorshipBrazilian research foundation CNPq
dc.description.sponsorshipBrazilian research foundation CAPES
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.date.available2017-11-13T13:54:11Z-
dc.date.accessioned2017-11-13T13:54:11Z-
dc.description.provenanceMade available in DSpace on 2017-11-13T13:54:11Z (GMT). No. of bitstreams: 1 000396347700001.pdf: 3648265 bytes, checksum: 551640edb696b8290c9e62fdfe001f7f (MD5) Previous issue date: 2017en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/329340-
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