Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/329340
Type: Artigo
Title: Maldi Imaging Mass Spectrometry Of Fresh Water Cyanobacteria: Spatial Distribution Of Toxins And Other Metabolites
MALDI imaging mass spectrometry of fresh water cyanobacteria: spatial distribution of toxins and other metabolites
Author: Sandonato, Beatriz B.
Santos, Vanessa G.
Luizete, Milena F.
Bronzel Jr., João L.
Eberlin, Marcos N.
Milagre, Humberto M. S.
Abstract: Cyanobacteria are among the most ancient forms of life, yet they are known to synthesize highly sophisticated defense molecules, such as the highly hepatotoxic cyclic peptides microcystins and nodularins produced by the genera Microcystis, Anabaena and Nodularia. These metabolites are released by cyanobacteria to water environments causing episodes of fatalities among animals and humans. To better understand the releasing of these metabolites, imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) was herein applied to determine the spatial distribution of such toxins directly on agar-based cultures. Other key metabolites such as aeruginosin 602 and the siderophore anachelin were also mapped in mixed cyanobacterial cultures, showing the great potential of IMS to spatially monitor the biochemical details of cyanobacterial defense and interactions.
Cyanobacteria are among the most ancient forms of life, yet they are known to synthesize highly sophisticated defense molecules, such as the highly hepatotoxic cyclic peptides microcystins and nodularins produced by the genera Microcystis, Anabaena and No
Subject: Cyanobacteria
Maldi-tof
Mass Spectrometry
Imaging
Cianobactéria
Espectrometria de massas por ionização e dessorção a laser assistida por matriz
Espectrometria de massa
Country: Brasil
Editor: Sociedade Brasileira de Química
Citation: Journal Of The Brazilian Chemical Society. Soc Brasileira Quimica, v. 28, p. 521 - 528, 2017.
Rights: aberto
Aberto
Identifier DOI: 10.5935/0103-5053.20160191
Address: http://www.scielo.br/scielo.php?pid=S0103-50532017000400521&script=sci_arttext
Date Issue: 2017
Appears in Collections:IQ - Artigos e Outros Documentos

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