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Type: Artigo
Title: Acute And Late Bartonella Henselae Murine Model Infection
Author: da Silva
Marilene Neves; Vieira-Damiani
Gislaine; Ericson
Marna Elise; Gupta
Kalpna; de Almeida
Amanda Roberta; Drummond
Marina Rovani; Benetti Soares
Tania Cristina; Lania
Bruno Grosselli; Gilioli
Rovilson; Neves Ferreira Velho
Paulo Eduardo
Abstract: Bartonella spp. are fastidious gram-negative neglected bacilli with worldwide distribution. They are able to cause intraerythrocytic and potentially fatal infection. Cats and dogs are reservoirs of some species of these agents. Blood-sucking arthropods are potential vectors. Our aim was to evaluate the blood, skin, liver, and spleen in BALB/c mice by using molecular tests and confocal microscopy to demonstrate Bartonella henselae infection in the bloodstream and organs after 4 and 21 days of intraperitoneally injected bacterial suspension. We demonstrate that the occurrence of infection in organs precedes the detectable infection in blood. Therefore, late manifestation in blood may be another challenge in early detection and diagnosis of B. henselae infection.
Subject: Bartonella
Editor: Mary Ann Liebert, Inc
New Rochelle
Citation: Vector-borne And Zoonotic Diseases. Mary Ann Liebert, Inc, v. 17, p. 206 - 208, 2017.
Rights: fechado
Identifier DOI: 10.1089/vbz.2016.2007
Date Issue: 2017
Appears in Collections:Unicamp - Artigos e Outros Documentos

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