Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/327782
Type: Artigo
Title: Liver Failure Following Biliopancreatic Diversions: A Narrative Review
Liver failure following biliopancreatic diversions: a narrative review
Title Alternative: Falência hepática após derivações biliopancreáticas: uma revisão narrativa
Author: Cazzo, E.
Pareja, J.C.
Chaim, E.A.
Abstract: Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions (BPDs) have also been implicated in several cases of acute and subacute liver failure. The aim here was to review the current available evidence on occurrences of liver failure following BPDs. DESIGN AND SETTING: Narrative review; bariatric surgery service of a public university hospital. METHODS: A review of the literature was conducted through an online search of medical databases. RESULTS: Associations between BPDs and liver failure have only infrequently been reported in the literature. However, they appear to be more than merely anecdotal. The pathophysiological mechanisms remain obscure, but they seem to be related to rapid weight loss, protein malnutrition, deficits of hepatotrophic factors, high circulating levels of free fatty acids and bacterial overgrowth in the bypassed bowel segments. Reversal of the BPD may ameliorate the liver impairment. CONCLUSIONS: Although infrequent, liver failure remains a concern following BPDs. Careful follow-up is required in individuals who undergo any BPD.
Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions
Subject: Liver Failure
Biliopancreatic Diversion
Bariatric Surgery
Obesity
Liver Diseases
Desvio Biliopancreático
Hepatopatias
Obesidade
Country: Brasil
Editor: Associação Paulista de Medicina
Citation: Sao Paulo Medical Journal. Associacao Paulista Medicina, v. 135, p. 66 - 70, 2017.
Rights: aberto
Aberto
Identifier DOI: 10.1590/1516-3180.2016.0129220616
Address: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802017000100066
Date Issue: 2017
Appears in Collections:FCM - Artigos e Outros Documentos

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