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Type: Artigo
Title: Tuning The Reactivity Of Sp1 Zinc Fingers With Platinum Complexes
Author: Du
Zhifeng; de Paiva
Raphael E. F.; Qu
Yun; Farrell
Abstract: cis-DDP presents reactivity towards the transcription factor Sp1-F3, as opposed to previous observations for Sp1-F2. Replacing the ammine ligands with the chelating ethylenediamine increases the reactivity giving a unique dinuclear {Pt(en)}(2)-bis(cysteine)-bridged product, confirmed by study of the binding sequence ACPECP.
Editor: Royal Soc Chemistry
Citation: Dalton Trasactions. Royal Soc Chemistry, v. 45, p. 8712 - 8716, 2016.
Rights: fechado
Identifier DOI: 10.1039/c6dt01128d
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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