Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/327554
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authoremailformiga@iqm.unicamp.brpt_BR
dc.typeArtigopt_BR
dc.titleEnhanced Performance Of A Metal-organic Framework Analogue To Mil-101(cr) Containing Amine Groups For Ibuprofen And Nimesulide Controlled Releaseen
dc.contributor.authorSilvapt_BR
dc.contributor.authorIrlene M. P.; Carvalhopt_BR
dc.contributor.authorMarcos A.; Oliveirapt_BR
dc.contributor.authorCintia S.; Profiriopt_BR
dc.contributor.authorDaniel M.; Ferreirapt_BR
dc.contributor.authorRicardo B.; Corbipt_BR
dc.contributor.authorPedro P.; Formigapt_BR
dc.contributor.authorAndre L. B.pt_BR
unicamp.authorFormiga, Andre L. B.] Univ Estadual Campinas, UNICAMP, Inst Chem, POB 6154, BR-13083970 Campinas, SP, Brazilpt_BR
unicamp.author.external[Silva, Irlene M. P.pt_BR
unicamp.author.externalCarvalho, Marcos A.pt_BR
unicamp.author.externalProfirio, Daniel M.pt_BR
unicamp.author.externalFerreira, Ricardo B.pt_BR
unicamp.author.externalCorbi, Pedro P.pt_BR
unicamp.author.external[Oliveira, Cintia S.] Univ Fed Sergipe, Dept Quim, BR-49100000 Sao Cristovao, SE, Brazilpt_BR
dc.subjectControlled Drug Releaseen
dc.subjectMil-101(cr)en
dc.subjectIbuprofenen
dc.subjectNimesulideen
dc.description.abstractIn order to improve the interaction of MIL-101(Cr) with ibuprofen (IBU) and nimesulide (NMS), its functionalization with NH2 groups was proposed. MIL-101(Cr) showed a good loading capacity of IBU and NMS (850 and 443 mg g(-1), respectively) and released 80% of IBU and 10% and NMS after 8 days. The 10% NH2-MIL-101(Cr) showed a higher loading capacity than MIL-101(Cr) (900 mg g(-1) for IBU and 563 mg g(-1) for NMS) and released lower amounts of IBU (70%) after 6 days and NMS (8%) after 8 days. The results show that the functionalization with NH2 groups improves the interactions between the materials and the drugs, which is of interest in the development of new controlled drug release devices. (C) 2016 Elsevier B.V. All rights reserved.en
dc.relation.ispartofInorganic Chemistry Communicationspt_BR
dc.publisherElsevier Science BVpt_BR
dc.publisherAmsterdampt_BR
dc.date.issued2016pt_BR
dc.date.monthofcirculationagospt_BR
dc.identifier.citationInorganic Chemistry Communications. Elsevier Science Bv, v. 70, p. 47 - 50, 2016.pt_BR
dc.language.isoEnglishpt_BR
dc.description.volume70pt_BR
dc.description.initialpage47pt_BR
dc.description.lastpage50pt_BR
dc.rightsfechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1387-7003pt_BR
dc.identifier.eissn1879-0259pt_BR
dc.identifier.wosidWOS:000380865300012pt_BR
dc.identifier.doi10.1016/j.inoche.2016.05.020pt_BR
dc.identifier.urlhttp://www-sciencedirect-com.ez88.periodicos.capes.gov.br/science/article/pii/S1387700316301526?via%3Dihubpt_BR
dc.date.available2017-11-13T13:16:29Z-
dc.date.accessioned2017-11-13T13:16:29Z-
dc.description.provenanceMade available in DSpace on 2017-11-13T13:16:29Z (GMT). No. of bitstreams: 1 000380865300012.pdf: 545444 bytes, checksum: 5438f64af88d9559612b6704a2e2faf3 (MD5) Previous issue date: 2016en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/327554-
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