Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/326503
Type: Book
Title: Post-translational Modifications And Rna-binding Proteins
Author: Lovci
Michael T.; Bengtson
Mario H.; Massirer
Katlin B.
Abstract: RNA-binding proteins affect cellular metabolic programs through development and in response to cellular stimuli. Though much work has been done to elucidate the roles of a handful of RNA-binding proteins and their effect on RNA metabolism, the progress of studies to understand the effects of post-translational modifications of this class of proteins is far from complete. This chapter summarizes the work that has been done to identify the consequence of post-translational modifications to some RNA-binding proteins. The effects of these modifications have been shown to increase the panoply of functions that a given RNA-binding protein can assume. We will survey the experimental methods that are used to identify the presence of several protein modifications and methods that attempt to discern the consequence of these modifications.
Subject: Rna-binding Proteins
Post-translational Modifications
Sumoylation
Ubiquitination
Phosphorylation
Editor: Springer Int Publishing
Cham
Rights: fechado
Identifier DOI: 10.1007/978-3-319-29073-7_12
Address: https://link-springer-com.ez88.periodicos.capes.gov.br/chapter/10.1007%2F978-3-319-29073-7_12
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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