Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/326238
Type: Artigo
Title: Volumetric Nasal Cavity Analysis In Children With Unilateral And Bilateral Cleft Lip And Palate
Author: Farzal
Zainab; Walsh
Jonathan; de Rezende Barbosa
Gabriella Lopes; Zdanski
Carlton J.; Davis
Stephanie D.; Superfine
Richard; Pimenta
Luiz A.; Kimbell
Julia S.; Drake
Amelia Fischer
Abstract: Children with cleft lip and palate (CLP) often suffer from nasal obstruction that may be related to effects on nasal volume. The objective of this study was to compare side: side volume ratios and nasal volume in patients with unilateral (UCLP) and bilateral (BCLP) clefts with age-matched controls. Study Design: Retrospective case-control study using three-dimensional (3D) nasal airway reconstructions. Methods: We analyzed 20 subjects (age range = 7-12 years) with UCLP and BCLP from a regional craniofacial center who underwent cone beam computed tomography (CT) prior to alveolar grafting. Ten multislice CT images from age-matched controls were also analyzed. Mimics software (Materialise, Plymouth, MI) was used to create 3D reconstructions of the main nasal cavity and compute total and side-specific nasal volumes. Subjects imaged during active nasal cycling phases were excluded. Results: There was no statistically significant difference in affected: unaffected side volume ratios in UCLP (p =.48) or left:right ratios in BCLP (P =.25) when compared to left: right ratios in controls. Mean overall nasal volumes were 9,932 +/- 1,807, 7,097 +/- 2,596, and 6,715 +/- 2,115 mm(3) for control, UCLP, and BCLP patients, respectively, with statistically significant volume decreases for both UCLP and BCLP subjects from controls (P <.05). Conclusions: This is the first study to analyze total nasal volumes in BCLP patients. Overall nasal volume is compromised in UCLP and BCLP by approximately 30%. Additionally, our finding of no major difference in side: side ratios in UCLP and BCLP compared to controls conflicts with pre-existing literature, likely due to exclusion of actively cycling scans and our measurement of the functional nasal cavity.
Subject: Nasal Volume
Unilateral Cleft Lip And Palate
Bilateral Cleft Lip And Palate
Editor: Wiley-Blackwell
Hoboken
Rights: fechado
Identifier DOI: 10.1002/lary.25543
Address: http://onlinelibrary-wiley-com.ez88.periodicos.capes.gov.br/doi/10.1002/lary.25543/full
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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