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Type: Artigo
Title: Cysts Within Otherwise Probably Benign Solid Breast Masses And The Risk Of Malignancy
Title Alternative: Cistos No Interior De Nódulo Mamários Benignos: Risco De Malignidade
Author: Jales
Rodrigo Menezes; Araujo
Karla Galvão; Sarian
Luis Otávio Zanata; Serra
Kátia Piton; Keppke
Helena; Francisco
Juliana; Derchain
Sophie Françoise Mauricette
Abstract: The objective of this study is to assess whether the largest cyst diameter is useful for BI-RADS ultrasonography classification of predominantly solid breast masses with an oval shape, circumscribed margins, and largest axis parallel to the skin, which, except for the cystic component, would be likely classified as benign. Methods This study received approval from the local institutional review board. From March 2009 to August 2014, we prospectively biopsied 170 breast masses from 164 women. We grouped the largest cyst and mass diameters according to histopathological diagnoses. We used Student's t-test, linear regression, and the area under the receiver operating characteristic curve (AUC) for statistical assessment. Results Histopathological examination revealed 143 (84%) benign and 27 (16%) malignant masses. The mean largest mass diameter was larger among malignant (mean standard deviation, 34.1 16.6 mm) than benign masses (24.7 16.7 mm) (P < 0.008). The mean largest cyst diameter was also larger among malignant (9.9 7.1 mm) than benign masses (4.6 3.6 mm) (P < 0.001). Agreement between measurements of the largest mass and cyst diameters was low (R2 = 0.26). AUC for the largest cyst diameter (0.78) was similar to the AUC for the largest mass diameter (0.69) ( p = 0.2). A largest cyst diameter < 3, 3 to < 11, and 11 mm had a positive predictive value of 0, 15, and 52%, respectively. Conclusion A largest cystic component < 3 mm identified within breast masses that show favorable characteristics may be considered clinically inconsequential in ultrasonography characterization. Conversely, masses with a largest cystic component 3 mm should be classified as BI-RADS-US category 4.
Subject: Breast Cancer
Breast Imaging Reporting And Data System
Breast Sonography
Circumscribed Masses
Complex Masses
Câncer De Mama
Ultrassonografia Mamária
Nódulos Circunscritos
Nódulos Complexos
Editor: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
Rights: aberto
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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