Please use this identifier to cite or link to this item:
Type: Artigo
Title: Effect Of Resveratrol On Periodontal Pathogens During Experimental Periodontitis In Rats
Author: Cirano
Fabiano Ribeiro; Casarin
Renato Correa Viana; Ribeiro
Fernanda Vieira; Casati
Marcio Zaffalon; Pimentel
Suzana Peres; Taiete
Tiago; Bernardi
Maria Martha
Abstract: The objective of this study was to investigate the antibacterial effect of resveratrol against putative periodontal pathogens during the progression of experimental periodontitis in rats. Periodontitis was induced in rats in one of the first molars chosen to receive a ligature. Animals were assigned to one of two groups: daily administration of the placebo solution (control group, n = 12) or 10 mg/Kg of resveratrol (RESV group, n = 12). The therapies were administered systemically for 30 days, for 19 days before periodontitis induction and then for another 11 days. Then, the presence and concentrations of Porphyromonas gingivalis, Tannerella forsythia and Aggregatibacter actinomycetemcomitans in the cotton ligatures collected from the first molars were evaluated using real-time PCR. Inter-group comparisons of the microbiological outcomes revealed that no differences were detected for P. gingivalis, T. forsythia and A. actinomycetemcomitans levels (p > 0.05). Continuous use of resveratrol did not promote additional benefits in microbiological outcomes during experimental periodontitis in rats.
Subject: Resveratrol
Alveolar Bone Loss
Anti-inflammatory Agents
Anti-bacterial Agents
Editor: Sociedade Brasileira de Pesquisa Odontológica - SBPqO
Citation: Brazilian Oral Research . Sociedade Brasileira De Pesquisa Odontológica - Sbpqo, v. 30, n. 1, p.
Rights: aberto
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
S1806-83242016000100318.pdf224.74 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.