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Type: Artigo
Title: Strategies To Evaluate The Impact Of Rectal Volume On Prostate Motion During Three-dimensional Conformal Radiotherapy For Prostate Cancer
Title Alternative: Avaliação Do Impacto Do Volume Retal Na Movimentação Da Próstata Durante Radioterapia Conformacional Para Câncer De Próstata
Author: Poli
Ana Paula Diniz Fortuna; Dias
Rodrigo Souza; Giordani
Adelmo José; Segreto
Helena Regina Comodo; Segreto
Roberto Araujo
Abstract: To evaluate the rectal volume influence on prostate motion during three-dimensional conformal radiotherapy (3D-CRT) for prostate cancer. Materials and Methods: Fifty-one patients with prostate cancer underwent a series of three computed tomography scans including an initial planning scan and two subsequent scans during 3D-CRT. The organs of interest were outlined. The prostate contour was compared with the initial CT images considering the anterior, posterior, superior, inferior and lateral edges of the organ. Variations in the anterior limits and volume of the rectum were assessed and correlated with prostate motion in the anteroposterior direction. Results: The maximum range of prostate motion was observed in the superoinferior direction, followed by the anteroposterior direction. A significant correlation was observed between prostate motion and rectal volume variation ( p = 0.037). A baseline rectal volume superior to 70 cm3 had a significant influence on the prostate motion in the anteroposterior direction ( p = 0.045). Conclusion: The present study showed a significant interfraction motion of the prostate during 3D-CRT with greatest variations in the superoinferior and anteroposterior directions, and that a large rectal volume influences the prostate motion with a cutoff value of 70 cm3. Therefore, the treatment of patients with a rectal volume > 70 cm3 should be re-planned with appropriate rectal preparation.
Subject: Rectal Volume
Prostate Cancer
Three-dimensional Conformal Radiotherapy
Volume Retal
Câncer De Próstata
Radioterapia Tridimensional Conformacional
Editor: Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
Rights: aberto
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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