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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigopt_BR
dc.titleEffect Of Fluoride Concentration On Reduction Of Enamel Demineralization According To The Cariogenic Challengeen
dc.contributor.authorNoronhapt_BR
dc.contributor.authorMayara dos Santos; Romãopt_BR
dc.contributor.authorDayse Andrade; Curypt_BR
dc.contributor.authorJaime Aparecido; Tabchourypt_BR
dc.contributor.authorCínthia Pereira Machadopt_BR
unicamp.authorUniversidade Estadual de Campinas, Piracicaba SP, Brazilpt_BR
dc.subjectDental Cariesen
dc.subjectDental Enamelen
dc.subjectFluoridesen
dc.subjectTooth Demineralizationen
dc.subjectToothpasteen
dc.description.abstractFluoride present in toothpaste at 1,100 µg/g is considered effective on caries control. However, under high cariogenic challenge due to increasing sugar exposure, higher fluoride concentration (5,000 µg/g) could be necessary to compensate the unbalance on caries process. This was tested in a pH-cycling regimen, which evaluated the effect of fluoride concentration relative to toothpaste on reduction of enamel demineralization under conditions of two levels of cariogenic challenge. Enamel slabs (n=20) were subjected to two pH-cycling regimens, simulating 8x and 16x/day sugar exposure and were treated with solutions containing: 0 (no fluoride), 275 or 1,250 µg F/mL, resulting in 6 treatment groups: 4-h/0-F; 8-h/0-F; 4-h/275-F; 8-h/275-F; 4-h/1,250-F and 8-h/1,250-F. The 275 and 1,250 µg F/mL concentrations simulate mouth salivary dilution when 1,100 and 5,000 µg/g toothpastes are used. Enamel demineralization was assessed by surface (%SHL) and cross-sectional hardness. Fluoride taken up by enamel was also evaluated. Data were analyzed by ANOVA one-way and Tukey's test. The treatment with 1,250 µg F/mL significantly reduced %SHL compared with 275 µg F/mL (p<0.05), irrespective the level of cariogenic challenge (4-h/1,250-F vs. 4-h/275-F and 8-h/1,250-F vs 8-h/275-F comparisons, respectively). These data were supported by fluoride concentration found in enamel. These findings suggest that higher fluoride concentrations could partly compensate the greater caries risk under higher cariogenic challenge due to increasing sugar exposure.en
dc.relation.ispartofBrazilian Dental Journalpt_BR
dc.publisherFundação Odontológica de Ribeirão Pretopt_BR
dc.date.issued2016pt_BR
dc.identifier.citationBrazilian Dental Journal. Fundação Odontológica De Ribeirão Preto, v. 27, n. 4, p. 393 - 398pt_BR
dc.language.isoInglespt_BR
dc.description.volume27pt_BR
dc.description.issuenumber4pt_BR
dc.description.firstpage393pt_BR
dc.description.lastpage398pt_BR
dc.rightsabertopt_BR
dc.sourceScielopt_BR
dc.identifier.issn0103-6440pt_BR
dc.identifier.idScieloS0103-64402016000400393pt_BR
dc.identifier.urlhttp://www.scielo.br/scielo.php?pid=S0103-64402016000400393&script=sci_abstract&tlng=ptpt_BR
dc.date.available2017-08-30T17:36:35Z-
dc.date.accessioned2017-08-30T17:36:35Z-
dc.description.provenanceMade available in DSpace on 2017-08-30T17:36:35Z (GMT). No. of bitstreams: 1 S0103-64402016000400393.pdf: 394284 bytes, checksum: 76e0c434a2da59749cce3fb8c457fdb5 (MD5) Previous issue date: 2016en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/324519-
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