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|Title:||Simulation Of In Vitro Digestion Coupled To Gastric And Intestinal Transport Models To Estimate Absorption Of Anthocyanins From Peel Powder Of Jabuticaba, Jamelão And Jambo Fruits|
|Author:||Marques Peixoto F.|
Galhardo Borguini R.
|Abstract:||The bioaccessibility of the anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits under gastro-intestinal conditions and their gastric and intestinal absorption was examined in order to estimate anthocyanin transport efficiency (ATE). Thus, in vitro digestion coupled to epithelium absorptive models (gastric MKN-28 and intestinal Caco-2) was applied independently for each phase. The bioaccessibility of anthocyanins after gastric digestion were 13% for jabuticaba, 45% for jambo and 65% for jamelão, whereas intestinal bioaccessibility were 10% for jabuticaba, 15% for jambo and 45% for jamelão. The assays showed that, applying the MKN-28 cell model, the ATE were 19.7, 9.7 and 14.1%, respectively, for jambo, jabuticaba, and jamelão powders, whereas using the Caco-2 cell model these results were 0.8, 0.2 and 0.3%, respectively. In conclusion gastric mucosa plays an important role in anthocyanin's absorption. © 2016 Elsevier Ltd.|
Cyanidin-3,5-o-diglucoside (pubchem Cid: 441688)
Cyanidin-3-o-glucoside (pubchem Cid: 92131208)
Delphinidin-3-o-glucoside (pubchem Cid: 443650)
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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