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Type: Artigo
Title: Myotonic Dystrophy Type 1: Frequency Of Ophthalmologic Findings
Title Alternative: Distrofia Miotônica Tipo 1: Frequência Dos Achados Oftalmológicos
Author: Ikeda K.S.
Iwabe-Marchese C.
França M.C.
Nucci A.
de Carvalho K.M.
Abstract: The purpose of the study was to evaluate the frequency of ophthalmologic abnormalities in a cohort of myotonic dystrophy type 1 (DM1) patients and to correlate them with motor function. We reviewed the pathophysiology of cataract and low intraocular pressure (IOP). Method: Patients were included after clinical and laboratory diagnosis and after signed informed consent. They were evaluated by Motor Function Measure scale, Portuguese version (MFM-P) and ophthalmic protocol. Results: We evaluated 42 patients aged 17 to 64 years (mean 40.7 ± 12.5), 22 of which were men. IOP (n = 41) was reduced in all but one. We found cataract or positivity for surgery in 38 (90.48%) and ptosis in 23 (54.76%). These signs but not IOP were significantly correlated with severity of motor dysfunction. Abnormalities in ocular motility and stereopsis were observed. Conclusion: Cataract and ptosis are frequent in DM1 and associated to motor dysfunction. Reduced IOP is also common, but appears not to be related with motor impairment. © 2016, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.
Subject: Cataract
Eyelid Ptosis
Intraocular Pressure
Motor Function Measure Scale
Myotonic Dystrophy Type 1
Portuguese Version
Editor: Associacao Arquivos de Neuro-Psiquiatria
Rights: aberto
Identifier DOI: 10.1590/0004-282X20150218
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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