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|Title:||Strategies To Evaluate The Impact Of Rectal Volume On Prostate Motion During Three-dimensional Conformal Radiotherapy For Prostate Cancer|
|Title Alternative:||Avaliação Do Impacto Do Volume Retal Na Movimentação Da Próstata Durante Radioterapia Conformacional Para Câncer De Prostate|
|Abstract:||To evaluate the rectal volume influence on prostate motion during three-dimensional conformal radiotherapy (3D-CRT) for prostate cancer. Materials and Methods: Fifty-one patients with prostate cancer underwent a series of three computed tomography scans including an initial planning scan and two subsequent scans during 3D-CRT. The organs of interest were outlined. The prostate contour was compared with the initial CT images considering the anterior, posterior, superior, inferior and lateral edges of the organ. Variations in the anterior limits and volume of the rectum were assessed and correlated with prostate motion in the anteroposterior direction. Results: The maximum range of prostate motion was observed in the superoinferior direction, followed by the anteroposterior direction. A significant correlation was observed between prostate motion and rectal volume variation (p = 0.037). A baseline rectal volume superior to 70 cm3 had a significant influence on the prostate motion in the anteroposterior direction (p = 0.045). Conclusion: The present study showed a significant interfraction motion of the prostate during 3D-CRT with greatest variations in the superoinferior and anteroposterior directions, and that a large rectal volume influences the prostate motion with a cutoff value of 70 cm3. Therefore, the treatment of patients with a rectal volume > 70 cm3 should be re-planned with appropriate rectal preparation. © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem|
Three-dimensional Conformal Radiotherapy
|Editor:||Colegio Brasileiro de Radiologia|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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