Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/320488
Type: Artigo de Periódico
Title: Contralateral Noise Stimulation Delays P300 Latency In School-aged Children
Author: Ubiali
T; Sanfins
MD; Borges
LR; Colella-Santos
MF
Abstract: The auditory cortex modulates auditory afferents through the olivocochlear system, which innervates the outer hair cells and the afferent neurons under the inner hair cells in the cochlea. Most of the studies that investigated the efferent activity in humans focused on evaluating the suppression of the otoacoustic emissions by stimulating the contralateral ear with noise, which assesses the activation of the medial olivocochlear bundle. The neurophysiology and the mechanisms involving efferent activity on higher regions of the auditory pathway, however, are still unknown. Also, the lack of studies investigating the effects of noise on human auditory cortex, especially in peadiatric population, points to the need for recording the late auditory potentials in noise conditions. Assessing the auditory efferents in schoolaged children is highly important due to some of its attributed functions such as selective attention and signal detection in noise, which are important abilities related to the development of language and academic skills. For this reason, the aim of the present study was to evaluate the effects of noise on P300 responses of children with normal hearing. Methods P300 was recorded in 27 children aged from 8 to 14 years with normal hearing in two conditions: with and whitout contralateral white noise stimulation. Results P300 latencies were significantly longer at the presence of contralateral noise. No significant changes were observed for the amplitude values. Conclusion Contralateral white noise stimulation delayed P300 latency in a group of school-aged children with normal hearing. These results suggest a possible influence of the medial olivocochlear activation on P300 responses under noise condition.
Subject: Medial Olivocochlear System
Auditory-evoked Potentials
Otoacoustic Emission
Cochlear Sensitivity
Inferior Colliculus
Sound Localization
Normal-hearing
Brain-stem
Modulation
Cortex
Editor: PUBLIC LIBRARY SCIENCE
Rights: aberto
Identifier DOI: 10.1371/journal.pone.0148360
Address: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148360
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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