Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/320240
Type: Artigo de Periódico
Title: Chemical Composition And Cytotoxic Activity Of The Essential Oils Of Cantinoa Stricta (benth.) Harley & Jfb Pastore (lamiaceae)
Author: Scharf
DR; Simionatto
EL; Carvalho
JE; Salvador
MJ; Santos
EP; Stefanello
MEA
Abstract: The essential oils from the leaves and flowers of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae) were obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The major components of both oils were caryophyllene oxide (leaf - 31.6%; flower - 21.7%) and cis-pinane (leaf -15.4%; flower - 9.7%). The flower oil also contained significant amounts of alpha-pinene (9.4%) and beta-pinene (9.1%). The oils were tested in vitro against U251 (glioma), UACC-62 (melanoma), MCF-7 (breast), NCI-H460 (lung), PC-3 (prostate), K-562 (leukemia) human cancer cell lines and against HaCat (no cancer cell), using the sulforhodamine B method. Both oils showed antiproliferative activity against all tested cells lines (TGI < 50 mu g/mL), with exception of K562 cells. The highest activity was observed against MCF-7 cell lines (TGI = 4.54-10.36 mu g/mL).
Subject: Lamiaceae
Cantinoa Stricta
Essential Oil
Caryophyllene Oxide
Cytotoxic Activity
Editor: ACG PUBLICATIONS
Rights: fechado
Identifier DOI: 
Address: http://connection.ebscohost.com/c/articles/108849401/chemical-composition-cytotoxic-activity-essential-oils-cantinoa-stricta-benth-harley-j-f-b-pastore-lamiaceae
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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