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|Type:||Artigo de Periódico|
|Title:||Chemical Composition And Cytotoxic Activity Of The Essential Oils Of Cantinoa Stricta (benth.) Harley & Jfb Pastore (lamiaceae)|
|Abstract:||The essential oils from the leaves and flowers of Cantinoa stricta (Benth.) Harley & J.F.B. Pastore (Lamiaceae) were obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The major components of both oils were caryophyllene oxide (leaf - 31.6%; flower - 21.7%) and cis-pinane (leaf -15.4%; flower - 9.7%). The flower oil also contained significant amounts of alpha-pinene (9.4%) and beta-pinene (9.1%). The oils were tested in vitro against U251 (glioma), UACC-62 (melanoma), MCF-7 (breast), NCI-H460 (lung), PC-3 (prostate), K-562 (leukemia) human cancer cell lines and against HaCat (no cancer cell), using the sulforhodamine B method. Both oils showed antiproliferative activity against all tested cells lines (TGI < 50 mu g/mL), with exception of K562 cells. The highest activity was observed against MCF-7 cell lines (TGI = 4.54-10.36 mu g/mL).|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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