Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/318985
Type: research-article
Title: Antimicrobial activity and substantivity of Uncaria tomentosa in infected root canal dentin
Title Alternative: 
Author: HERRERA
Daniel Rodrigo; DURAND-RAMIREZ
Jorge Enrique; FALCÃO
Amanda; SILVA
Emmanuel João Leal Nogueira da; SANTOS
Elizabete Brasil dos; GOMES
Brenda Paula Figueiredo de Almeida
Abstract: The aim of this study was to analyze the antimicrobial activity and substantivity of Uncaria tomentosa Willd DC (cat s claw, CC) in root dentin contaminated with Enterococcus faecalis. Forty-eight human premolars were contaminated with E. faecalis (ATCC 29212) and randomly divided into four groups according to the irrigant used during chemomechanical preparation (CMP): CC group: 2% CC gel; CHX group: 2% chlorhexidine digluconate gel (CHX); NaOCl group: 5.25% sodium hypochlorite (NaOCl); and SS group: sterile saline (SS). Microbiological samples were collected before (S1) and after (S2) CMP and after 7 days (S3). Colony-forming units (CFU/mL) at the different sampling times and comparisons among the groups were statistically analyzed by Wilcoxon and Kruskal-Wallis tests (p < 0.05). Significant bacterial reduction was achieved in all groups after CMP (p < 0.05). Results show no significant difference between S3 and S2 (p > 0.05) in the CC and CHX groups. Bacterial load was higher in S3 than in S2 samples (p < 0.05) in the NaOCl and SS groups. Our results suggest antibacterial effect of 2% CC gel against E. faecalis in infected dentin, in addition to antibacterial substantivity of 2% CC and 2% CHX up to 7 days.
Citation: Brazilian Oral Research, 30, 12016.
Rights: aberto
Identifier DOI: 10.1590/1807-3107BOR-2016.vol30.0061
Address: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242016000100241
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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