Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/31253
Type: Artigo de periódico
Title: Hospital strain colonization by Staphylococcus epidermidis
Author: Blum-Menezes, D.
Bratfich, O.J.
Padoveze, M.C.
Moretti, M.L.
Abstract: The skin and mucous membranes of healthy subjects are colonized by strains of Staphylococcus epidermidis showing a high diversity of genomic DNA polymorphisms. Prolonged hospitalization and the use of invasive procedures promote changes in the microbiota with subsequent colonization by hospital strains. We report here a patient with prolonged hospitalization due to chronic pancreatitis who was treated with multiple antibiotics, invasive procedures and abdominal surgery. We studied the dynamics of skin colonization by S. epidermidis leading to the development of catheter-related infections and compared the genotypic profile of clinical and microbiota strains by pulsed field gel electrophoresis. During hospitalization, the normal S. epidermidis skin microbiota exhibiting a polymorphic genomic DNA profile was replaced with a hospital-acquired biofilm-producer S. epidermidis strain that subsequently caused repetitive catheter-related infections.
Subject: Staphylococcus epidermidis
Microbiota
Biofilm
Central venous catheter
Editor: Associação Brasileira de Divulgação Científica
Rights: aberto
Identifier DOI: 10.1590/S0100-879X2009000300011
Address: http://dx.doi.org/10.1590/S0100-879X2009000300011
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300011
Date Issue: 1-Mar-2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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