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Type: Artigo de periódico
Title: Improved method to obtain pfaffic acid as a marker for quality control
Author: Rodrigues, Marili Villa Nova
Vedovello, Amanda
Rodrigues, Rodney Alexandre Ferreira
Montanari Junior, Ilio
Rehder, Vera Lucia Garcia
Abstract: Pfaffic acid, a marker of Hebanthe eriantha (Brazilian ginseng), was first isolated in 1983 but is not yet commercially available. This lack of availability compromises the quality control of this plant and its derivatives. This paper proposes a process for pfaffic acid isolation from roots of H. eriantha at a purity suitable for analytical purposes. The steps involved in this process included extraction, hydrolysis, fractionation and purification by preparative HPLC. This process led to isolation of pfaffic acid with a chromatographic purity of 98.5% in a 0.25% yield from dried roots of H. eriantha; this yield is more than forty times higher than that of the current method in the literature.
Subject: pfaffic acid
Hebanthe eriantha
Pfaffia paniculata
Editor: Sociedade Brasileira de Química
Rights: aberto
Identifier DOI: 10.1590/S0100-40422013000500019
Date Issue: 1-Jan-2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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