Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/27279
Type: Artigo de periódico
Title: Transfusão de plaquetas: do empirismo ao embasamento científico
Title Alternative: Platelet transfusion: from empiricism to scientific evidence
Author: Ferreira, Aline A.
Soares, Sheila
Castro, Vagner de
Moraes-Souza, Helio
Abstract: Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion tests that may compromise transfusion safety is still observed at transfusion agencies in the fringes of the blood transfusion therapy system. Additionally, although high rates of platelet transfusion refractoriness and significant rates of alloimmunization have been demonstrated in the international literature, few Brazilian centers have been concerned with the study of platelet alloimmunization and even fewer centers have evaluated the efficacy of platelet concentrate transfusion. As more than one million Brazilians, including many repeat blood donors, are listed in the National Bone Marrow Donor Registry (Redome), why not grant transfusion therapy services access to the HLA typing of these blood and marrow donors after obtaining their consent? And why not make use of the Redome data to evaluate the HLA compatibility of donors for alloimmunized patients who are candidates for bone marrow transfusion and who have already been typed? These measures, together with the identification of ABO and HPA antigens, will permit a complete assessment of platelet immunology, will guarantee the transfusion safety of this blood component, and will put Brazil at the same level as the so-called developed countries in terms of transfusion medicine.
Subject: Platelet transfusion
platelets
hemotherapy
globins
quality control
Editor: Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea
Rights: aberto
Identifier DOI: 10.1590/S1516-84842010000400011
Address: http://dx.doi.org/10.1590/S1516-84842010000400011
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842010000400011
Date Issue: 1-Jan-2010
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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