Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/26428
Type: Artigo de periódico
Title: Osteonecrose dos maxilares associada ao uso de bisfosfonatos
Title Alternative: Bisphosphonate-related osteonecrosis of the jaws
Author: Passeri, Luis Augusto
Bértolo, Manoel Barros
Abuabara, Allan
Abstract: Bisphosphonates are potent inhibitors of bone resorption, and are used in the treatment of osteoporosis and other diseases that cause bone mass loss, such as Paget's disease, bone metastases, and multiple myeloma, to prevent pathological fractures. Since 2003, avascular osteonecrosis of the jaw has been associated with the use of bisphosphonates, mainly intravenous. According to the literature, the occurrence of osteonecrosis of the jaw has ranged from 0.8% to 12% of the patients on bisphosphonates, most of them on prolonged use. Physicians and odontologists should be aware of that potential complication in dental treatment.
Os bisfosfonatos são potentes inibidores da reabsorção óssea e são utilizados no tratamento da osteoporose e de outras doenças que causam a perda de massa óssea, como doença de Paget, metástases ósseas e mieloma múltiplo, prevenindo fraturas patológicas. Desde 2003, estudos associam osteonecrose avascular dos ossos maxilares a seu uso, principalmente intravenoso. Na literatura, há relatos de ocorrência variando de 0,8% a 12%, dos pacientes, na sua maioria em uso prolongado. Médicos e dentistas devem estar cientes dessa potencial complicação no tratamento odontológico.
Subject: Osteonecrose
doenças maxilares
osteoporose
osteonecrosis
maxillary diseases
osteoporosis
Editor: Sociedade Brasileira de Reumatologia
Rights: aberto
Identifier DOI: 10.1590/S0482-50042011000400012
Address: http://dx.doi.org/10.1590/S0482-50042011000400012
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042011000400012
Date Issue: 1-Aug-2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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