Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/26392
Type: Artigo de periódico
Title: Coexistência de hipotiroidismo e polimiosite
Title Alternative: Coexistence of hypothyroidism and polymyositis
Author: Singh, Maize Fernanda Bonim
Fernandes, Sandra Regina M.
Costallat, Lilian Tereza Lavras
Bértolo, Manoel Barros
Queiroz, Luciano de Souza
Samara, Adil Muhib
Abstract: Patients with hypothyroidism frequently present with musculoskeletal complaints and elevated serum levels of muscle enzymes, like creatine kinase (CK). With adequate hormonal treatment, the maintenance of high values of CK and muscle symptoms are uncommon. This work reports a 47-year-old woman with hypothyroidism, proximal muscle weakness and increased CK, who didn't improved with levothyroxine treatment. The diagnosis of polymyositis was based on electromyography and muscle biopsy. After treatment with prednisone plus methotrexate and increase of the levothyroxine dose, there were a clinical improvement and a normalization of CK values.
Pacientes com hipotiroidismo freqüentemente apresentam sintomas músculo-esqueléticos e aumento de enzimas musculares, como a creatinaquinase (CK). Com o tratamento hormonal adequado é incomum ocorrer grandes aumentos de CK e manutenção de queixas musculares. Este trabalho relata o caso de uma paciente com hipotiroidismo, queixa de fraqueza muscular proximal e aumento de CK, sem melhora clínica com uso de levotiroxina. O diagnóstico de polimiosite foi confirmado por eletroneuromiografia e biópsia muscular. Após tratamento com prednisona e metotrexato, além de adequação da dose de levotiroxina, houve melhora clínica significativa e normalização da CK.
Subject: hipotiroidismo
polimiosite
miopatias
fraqueza muscular
Hypothyroidism
polymyositis
myopathies
muscle weakness
Editor: Sociedade Brasileira de Reumatologia
Rights: aberto
Identifier DOI: 10.1590/S0482-50042003000500012
Address: http://dx.doi.org/10.1590/S0482-50042003000500012
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042003000500012
Date Issue: 1-Oct-2003
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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