Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/26053
Type: Artigo de periódico
Title: DYNAMIC MODELLING AND ADVANCED PREDICTIVE CONTROL OF A CONTINUOUS PROCESS OF ENZYME PURIFICATION
Author: Dechechi, E.C.
Martins, M.I.
Maciel Filho, R.
Maugeri, F.
Abstract: A dynamic mathematical model, simulation and computer control of a Continuous Affinity Recycle Extraction (CARE) process, a protein purification technique based on protein adsorption on solid-phase adsorbents is described in this work. This process, consisting of three reactors, is a multivariable process with considerable time delay in the on-line analyses of the controlled variable. An advanced predictive control configuration, specifically the Dynamic Matrix Control (DMC), was applied. The DMC algorithm was applied in process schemes where the aim was to maintain constant the enzyme concentration in the outlet of the third reactor. The performance of the DMC controller was analyzed in the feed-flow disturbances and the results are presented.
Subject: Dynamic model
protein
DMC
Editor: Brazilian Society of Chemical Engineering
Rights: aberto
Identifier DOI: 10.1590/S0104-66321997000400018
Address: http://dx.doi.org/10.1590/S0104-66321997000400018
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66321997000400018
Date Issue: 1-Dec-1997
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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