Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/25076
Type: Artigo de periódico
Title: Flow microcalorimetric measurements of the antibacterial activity of the homologous series m-alkoxyphenols and p-hydroxybenzoates on Escherichia coli
Author: Volpe, P.L.O
Abstract: Antibacterial activity of two homologous series (m-alkoxyphenols and p-hydroxybenzoates) was studied in vitro by the respiration of Escherichia coli using flow microcalorimetry. Results for both series showed a linear relationship between log(dose) and the calorimetric response (CR). Analysis of the data allowed the identification of contributions for the derived bioactivity from the parent structures (the molecule minus n-CH2 groups present in the side-chain) and the lipophilic groups, CH2.
A atividade antibacteriana dos membros de duas séries homólogas (m-alcoxifenóis e p-hidroxibenzoatos de alquila) foi estudada in vitro sobre a respiração da Escherichia coli usando microcalorimetria de fluxo. Os resultados para ambas as séries mostraram uma relação linear entre log(dose) e a resposta calorimétrica (RC). Análise dos dados permitiu a identificação de contribuições de bioatividade concernente a estrutura matriz (a molécula menos os grupos n-CH2 presentes na cadeia lateral) e a grupos lipofílicos, CH2.
Subject: biological microcalorimetry
calorimetric response
homologous series
Editor: Sociedade Brasileira de Química
Rights: aberto
Identifier DOI: 10.1590/S0103-50531997000400005
Address: http://dx.doi.org/10.1590/S0103-50531997000400005
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50531997000400005
Date Issue: 1-Jan-1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
S0103-50531997000400005.pdf156.22 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.