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Type: Artigo
Title: Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues
Author: Carneiro, Vânia M.T.
Trivella, Daniela B.B.
Scorsato, Valéria
Beraldo, Viviane L.
Dias, Mariana P.
Sobreira, Tiago J.P.
Aparicio, Ricardo
Pilli, Ronaldo A.
Abstract: RK-682 (1) is a natural product known to selectively inhibit protein tyrosine phosphatases (PTPases) and is used commercially as a positive control for phosphatase inhibition in in vitro assays. Protein phosphatases are involved in several human diseases
Subject: Proteína tirosina fosfatase
Inibidores de fosfatases
Inibição enzimática
Country: França
Editor: Elsevier
Citation: Is Rk-682 A Promiscuous Enzyme Inhibitor? Synthesis And In Vitro Evaluation Of Protein Tyrosine Phosphatase Inhibition Of Racemic Rk-682 And Analogues. Elsevier France-editions Scientifiques Medicales Elsevier, v. 97, p. 42-54 Jun-2015.
Rights: Fechado
Identifier DOI: 10.1016/j.ejmech.2015.04.036
Date Issue: 2015
Appears in Collections:IQ - Artigos e Outros Documentos

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