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Type: Artigo de periódico
Title: Urised As An Alternative To Phase-contrast Microscopy In The Differentiation Between Glomerular And Non-glomerular Hematuria
Author: Bottini
Paula V.; Andreguetto
Bruna D.; Krempser
Kelly; Lauand
Jose Ricardo; Garlipp
Celia R.
Abstract: Background: Differentiation between glomerular and non-glomerular hematuria by observation of the erythrocyte morphology using phase-contrast is a time-consuming and labor-intensive procedure that requires skilled personnel. This paper has the purpose to evaluate the performance of UriSed (also called sediMAX (R) in some countries) as an alternative to the phase-contrast microscopic analysis of erythrocyte morphology. Methods: 312 urine samples with hematuria were analyzed by UriSed and by phase-contrast microscopy. Based on the presence of codocytes and/or acanthocytes, samples were classified as non-glomerular and glomerular. Kappa correlation was used to assess the agreement between both methods. Results: Our data showed excellent agreement between erythrocyte morphology analyzed by both methods (r = 0.974, kappa = 0.9484, p <0.001) with only 8 samples presenting discordant results. Conclusions: UriSed proved to be a precise and accurate alternative to the gold standard phase-contrast microscopy.
Subject: Erythrocyte Morphology
Urine Sediment
Dysmorphic Erythrocytes
Rights: aberto
Identifier DOI: 10.7754/Clin.Lab.2014.141118
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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