Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/242832
Type: Artigo de periódico
Title: Hybrid Encapsulation Structures Based On Beta-carotene-loaded Nanoliposomes Within Electrospun Fibers
Author: de Freitas Zompero
Rafael Henrique; Lopez-Rubio
Amparo; de Pinho
Samantha Cristina; Lagaron
Jose Maria; de la Torre
Lucimara Gaziola
Abstract: Hybrid encapsulation structures based on beta-carotene-loaded nanoliposomes incorporated within the polymeric ultrathin fibers produced through electrospinning were developed to improve the photostability of the antioxidant. These novel materials were intended to incorporate beta-carotene into water-based food formulations, overcoming the existing limitations associated with its hydrophobic character. Initially, both empty and antioxidant-loaded nanoliposomes were developed and incorporated into polyvinyl alcohol (PVOH) and polyethylene oxide (PEO) solutions. The changes in the solution properties were evaluated to determine their effects on the electrospinning processing. The mixed polymer solutions were subsequently electrospun to produce hybrid nanoliposome-loaded ultrathin fibers. FTIR analysis confirmed the presence of phospholipid molecules inside the electrospun fibers. These ultrathin fibers were evaluated regarding their morphology, diameter, internal beta-carotene distribution and stability against UV irradiation. Liposomal release studies from the electrospun fibers were also undertaken, confirming the presence of the liposomal structures after dissolving the electrospun fibers in water. (C) 2015 Published by Elsevier B.V.
Subject: Zein Prolamine
Nanofibers
Liposomes
Antioxidants
Delivery
Cancer
Country: AMSTERDAM
Editor: ELSEVIER SCIENCE BV
Rights: embargo
Identifier DOI: 10.1016/j.colsurfb.2015.03.015
Address: http://www.sciencedirect.com/science/article/pii/S0927776515001496
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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