Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: Prevalence Of Treponema Species Detected In Endodontic Infections: Systematic Review And Meta-regression Analysis
Author: Leite
Fabio R. M.; Nascimento
Gustavo G.; Demarco
Flavio F.; Gomes
Brenda P. F. A.; Pucci
Cesar R.; Martinho
Frederico C.
Abstract: Introduction: This systematic review and meta-regression analysis aimed to calculate a combined prevalence estimate and evaluate the prevalence of different Treponema species in primary and secondary endodontic infections, including symptomatic and asymptomatic eases. Methods: The MEDLINE/PubMed, Embase, Scielo, Web of Knowledge, and Scopus data-bases were searched without starting date restriction up to and including March 2014. Only reports in English were included. The selected literature was reviewed by 2 authors and classified as suitable or not to be included in this review. Lists were compared, and, in case of disagreements, decisions were made after a discussion based on inclusion and exclusion criteria. A pooled prevalence of Treponema species in endodontic infections was estimated. Additionally, a meta-regression analysis was performed. Results: Among the 265 articles identified in the initial search, only 51 were included in the final analysis. The studies were classified into 2 different groups according to the type of endodontic infection and whether it was an exclusively primary/secondary study (n = 36) or a primary/secondary comparison (n = 15). The pooled prevalence of Treponema species was 41.5% (95% confidence interval, 35.9-47.0). In the multivariate model of meta-regression analysis, primary endodontic infections (P < .001), acute apical abscess, symptomatic apical periodontitis (P < .001), and concomitant presence of 2 or more species (P = .028) explained the heterogeneity regarding the prevalence rates of Treponema species. Conclusions: Our findings suggest that Treponema species are important pathogens involved in endodontic infections, particularly in cases of primary and acute infections.
Subject: Polymerase-chain-reaction
Dna-dna Hybridization
Root-filled Teeth
Acute Apical Abscesses
Pcr-based Identification
Putative Oral Pathogens
Periapical Lesions
Red Complex
Country: NEW YORK
Rights: embargo
Identifier DOI: 10.1016/j.joen.2015.01.020
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
wos_000354597200002.pdf428.92 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.