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dc.typeArtigo de periódicopt_BR
dc.titleCollaborative Brazilian Pediatric Renal Transplant Registry (cobrazped-rtx): A Report From 2004 To 2013pt_BR
dc.contributor.authorC.; Pestanapt_BR
dc.contributor.authorJ. M.; Martinspt_BR
dc.contributor.authorS.; Nogueirapt_BR
dc.contributor.authorP.; Barrospt_BR
dc.contributor.authorV.; Rohdept_BR
dc.contributor.authorR.; Camargopt_BR
dc.contributor.authorM.; Feltranpt_BR
dc.contributor.authorL.; Esmeraldopt_BR
dc.contributor.authorR.; Carvalhopt_BR
dc.contributor.authorR.; Schvartsmanpt_BR
dc.contributor.authorB.; Vaisbichpt_BR
dc.contributor.authorM.; Watanabept_BR
dc.contributor.authorA.; Cunhapt_BR
dc.contributor.authorM.; Menesespt_BR
dc.contributor.authorR.; Pratespt_BR
dc.contributor.authorL.; Belangeropt_BR
dc.contributor.authorV.; Palmapt_BR
dc.contributor.authorL.; Carvalhopt_BR
dc.contributor.authorD.; Matukpt_BR
dc.contributor.authorT.; Beninipt_BR
dc.contributor.authorV.; Laranjopt_BR
dc.contributor.authorS.; Abbud-Filhopt_BR
dc.contributor.authorM.; Charpiotpt_BR
dc.contributor.authorI. M. M.; Ramalhopt_BR
dc.contributor.authorH. J.; Limapt_BR
dc.contributor.authorE.; Penidopt_BR
dc.contributor.authorJ.; Andradept_BR
dc.contributor.authorC.; Gesteirapt_BR
dc.contributor.authorM.; Tavarespt_BR
dc.contributor.authorM.; Penidopt_BR
dc.contributor.authorM.; De Souzapt_BR
dc.contributor.authorV.; Wagnerpt_BR
unicamp.authorPalma, L.] Univ Estadual Campinas, Pediat Nephrol Unit, Campinas, SP, Brazilpt_BR[Garcia,,, R.] Univ Ciencias Saude Porto Alegre, Hosp Crianca Santo Antonio Santa Casa, Pediat Nephrol Unit, Porto Alegre, RS, Brazilpt[Pestana, J.,, P.] Univ Fed Sao Paulo, Hosp Rim, Div Nephrol, Sao Paulo, Brazilpt[Camargo,, L.] Hosp Samaritano Sao Paulo, Pediat Nephrol Unit, Sao Paulo, Brazilpt[Esmeraldo,, R.] Hosp Geral Fortaleza, Transplant Unit, Fortaleza, Ceara, Brazilpt[Schvartsman,,, A.] Univ Sao Paulo, Fac Med, Hosp Clin, Inst Crianca,Pediat Nephrol Unit, Sao Paulo, Brazilpt[Cunha,, R.] Hosp Pequeno Principe, Pediat Nephrol Unit, Curitiba, Parana, Brazilpt[Prates,,[Carvalho,, T.] Hosp Fed Bonsucesso, Transplant Unit, Rio De Janeiro, Brazilpt[Benini,, S.] Santa Casa Sao Paulo, Pediat Nephrol Unit, Sao Paulo, Brazilpt[Abbud-Filho,, I. M., H. J.] Hosp Base Sao Jose Rio preto, Transplant Unit, S J Rio Preto, Brazilpt[Abbud-Filho,, H. J.] Inst Urol Nefrol Sao Jose Rio Preto, S J Rio Preto, Brazilpt[Lima,, J.] Univ Fed Minas Gerais, Hosp Clin, Pediat Nephrol Unit, Belo Horizonte, MG, Brazilpt[Andrade,, M.] Hosp Ana Neri, Pediat Nephrol Unit, Salvador, BA, Brazilpt[Tavares,, M.] Santa Casa Belo Horizonte, Pediat Nephrol Unit, Belo Horizonte, MG, Brazilpt[De Souza,, M.] Univ Fed Rio Grande do Sul, Programa Pos Grad Saude Crianca Adolescente, Porto Alegre, RS, Brazilpt[De Souza, V.] Univ Caxias do Sul, Caxias Do Sul, Brazilpt
dc.description.abstractBackground. The Collaborative Brazilian Pediatric Renal Transplant Registry started in 2004 as a multicenter initiative aiming to analyze, report, and share the results of pediatric kidney transplantation in Brazil. Data from all pediatric kidney transplants performed between January 2004 and December 2013 were recorded electronically and periodically updated. All patients under 18 years old from the participating centers were enrolled. Demographic data, etiology of chronic kidney disease, and patient and graft survival were analyzed. From a total of 2443 pediatric kidney transplants performed in Brazil during the study period, we report data from 1751 pediatric renal transplants performed in 13 centers enrolled in the collaborative study. Median age at transplantation was 12.4 years, and most of recipients were male (56%). The most common underlying renal etiologies were obstructive uropathy (31%) and glomerulopathy (26%). Methods. According to donor source, 1155 (66%) of transplants were performed with deceased donors (DD). Initial immunosuppression consisted mainly of tacrolimus, mycophenolate, steroids, and induction therapy with anti-IL-2R antibodies. Results. One-year graft survival (death-censored) was 93% and 90% (log rank test, P < .01), respectively, for living donor (LD) and DD. Graft losses (15%) were most frequently caused by vascular thrombosis, chronic allograft nephropathy, death with functioning kidney, acute rejection, and recurrent renal disease. Recipients of DD had 2.02 (95% confidence interval: 1.14-3.59) times the hazard of graft loss compared with those of LD (P = .015). Patient survival rates at 1 and 5 years were 98% and 97% for LD and 97% and 93% for DD, respectively. The mortality rate was 3.8%, mainly as the result of infection and cardiovascular disease. Conclusions. The results of this collaborative pediatric transplant study are comparable to international registries. Our effort has been able to maintain an exchange of information, both among the participating centers and with other international registries.en
dc.publisher.countryNEW YORKpt_BR
dc.identifier.citationCollaborative Brazilian Pediatric Renal Transplant Registry (cobrazped-rtx): A Report From 2004 To 2013. Elsevier Science Inc, v. 47, p. 950-953 MAY-2015.pt_BR
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