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Type: Artigo de periódico
Title: Novel Natural Food Colourant G8000 Benefits Ldl- And Hdl-cholesterol In Humans
Author: Peres
Rogerio Correa; Boiago Golluecke
Andrea Pitelli; Soares
Clayton; Machado
Patricia; Viveiros Filho
Vitor; Rocha
Silvana; Morais
Damila Rodrigues; Bataglion
Giovana Anceski; Eberlin
Marcos Nogueira; Ribeiro
Daniel Araki
Abstract: The aim of this study was to investigate the phenolic composition of a natural food colourant (G8000 (TM)) as well as its effects on plasma markers after 28-day consumption by healthy individuals at a dietary dose (70 g). Parameters of total cholesterol and its fractions, triglycerides and plasma enzymes biomarkers of muscle injury were measured. Major compounds identified in G8000 (TM) by ESI-MS showed the presence of anthocyanins, organic acids, phenolic acids as well as monosaccharides. HDL levels significantly increased from 43 +/- 10.2 mg/dL to 95 +/- 16.9 mg/dL. LDL levels significantly decreased from 110 +/- 40.9 mg/dL to 69 +/- 39 mg/dL (p<0.001). No significant statistical differences (p>0.05) were observed for total cholesterol, triglycerides and VLDL. After the intake, plasma enzyme CK-MB decreased from 20 +/- 12.1 U/L to 10 +/- 1.9 U/L while LDH levels increased from 275 +/- 124.4 U/L to 317 +/- 114.7 U/L (p<0.005). No significant differences were observed for CK levels. Taken together, dietary intake of natural colourant G8000 (TM) was able to exert beneficial effects on atherosclerosis biomarkers.
Subject: Acid-induced-colitis
Grape Juice
Red Wine
Oxidative Stress
French Paradox
Male Rats
Rights: embargo
Identifier DOI: 10.3109/09637486.2015.1028906
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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