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Type: Artigo de periódico
Title: Role of Tamm-Horsfall protein in the binding and in vivo phagocytosis of type 1 fimbriated Escherichia coli by mouse peritoneal macrophages
Author: Bastos, A.C.S.C.
Santos, L.B.
Tamashiro, W.M.S.C.
Yamada, A.T.
Oliveira, U.M.
Yano, T.
Abstract: Tamm-Horsfall glycoprotein (THP) contains manno-oligosaccharides that are recognized by type 1 fimbriae (F1) of Escherichia coli. In the present study, we examined the in vivo phagocytic activity of mouse peritoneal macrophages after treatment of bacteria with THP. At low THP concentrations (12.5 µg/ml and 50 µg/ml) no significant difference was observed in the phagocytosis of E. coli F1+. However, at high THP concentrations (500 µg/ml and 1250 µg/ml) we obtained a reduction of bacterial phagocytosis by mouse peritoneal macrophages.
Subject: Tamm-Horsfall protein
type 1 fimbriated E. coli
Editor: Associação Brasileira de Divulgação Científica
Rights: aberto
Identifier DOI: 10.1590/S0100-879X2001000700011
Date Issue: 1-Jul-2001
Appears in Collections:Unicamp - Artigos e Outros Documentos

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