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Type: Artigo de periódico
Title: Lomefloxacin Degradation: Antimicrobial Activity, Toxicity And Byproducts
Author: de Oliveira
Amanda M. D.; Maniero
Milena G.; Guimaraes
Jose R.
Abstract: Lomefloxacin (LOM) is an important antimicrobial drug. It has been detected in aqueous matrices in several countries. Its continuous introduction into the environment is a potential risk to aquatic and terrestrial organisms. The aim of this study was to evaluate the degradation of LOM by photolysis, peroxidation, and peroxidation assisted by ultraviolet radiation; moreover, the residual antimicrobial activity, the toxicity, and the byproducts formed during degradation processes were evaluated. Peroxidation was inefficient for LOM degradation and was not able to reduce antimicrobial activity. Both photolysis and UV/H2O2 were able to degrade more than 95% of LOM in 60 min (radiation dose of 5267 mJ cm(-2)). However, toxicity increased while these processes were being applied. For all processes evaluated, antimicrobial activity was still detected in the solution after 60 min of testing. Four byproducts were identified: m/z 332, 336, 348, and 350.
Subject: Tandem Mass-spectrometry
Sewage-treatment Plant
Aquatic Environment
Fluoroquinolone Antibiotics
Country: DUNDAS
Citation: Lomefloxacin Degradation: Antimicrobial Activity, Toxicity And Byproducts. Science & Technology Network Inc, v. 18, p. 211-220 JUL-2015.
Rights: fechado
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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