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Type: Artigo de periódico
Title: Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
Author: Cabral, Rodrigo S.
Sartori, Maura C.
Cordeiro, Ines
Queiroga, Carmen L.
Eberlin, Marcos N.
Lago, Joao H. G.
Moreno, Paulo R. H.
Young, Maria C. M.
Abstract: Conchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguara, is a native and endemic tree from Sao Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), gamma-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5).
Subject: acetylcholinesterase inhibitors
Conchocarpus fontanesianus
Country: Brazil
Editor: Soc Brasileira Farmacognosia
Citation: Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy. Soc Brasileira Farmacognosia, v.22, n.2, p.374-380, 2012
Rights: aberto
Identifier DOI: 10.1590/S0102-695X2011005000219
Date Issue: 2012
Appears in Collections:CPQBA - Artigos e Outros Documentos

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