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Type: Artigo de periódico
Title: Desenvolvimento e validação de metodologia analítica por CLAE-IR para determinação de artemisinina em Artemisia annua L
Title Alternative: Development and validation of analytical methodology by HPLC-IR for evaluation of artemisinin on Artemisa annua L
Author: Celeghini, Renata Maria dos Santos
Sousa, Ilza Maria de Oliveira
Silva, Ana Paula da
Rodrigues, Rodney Alexandre Ferreira
Foglio, Mary Ann
Abstract: The aim of this work was to develop and validate an analytical methodology for determination of artemisinin used as antimalaric. The method was based on high performace liquid chromatography, using a CN column with mobile phase composed of methanol : H2O 50:50 (V/V). The results showed that the method presented linearity from 50 to 1500 µg/mL. It was considered selective, accurate, precise according to the specific resolution from ANVISA, the Brazilian regulatory agency.
Subject: Artemisia annua L.
liquid chromatographic
Editor: Sociedade Brasileira de Química
Rights: aberto
Identifier DOI: 10.1590/S0100-40422009000400009
Date Issue: 1-Jan-2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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