Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/23826
Type: Artigo de periódico
Title: Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)
Author: Costa, Emmanoel Vilaça
Pinheiro, Maria Lúcia Belém
Silva, Jefferson Rocha de Andrade
Maia, Beatriz Helena Lameiro de Noronha Sales
Duarte, Marta Cristina Teixeira
Amaral, Ana Cláudia Fernandes
Machado, Gérzia Maria de Carvalho
Leon, Leonor Laura
Abstract: bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.
Subject: Annona foetida
antimicrobial and antileishmanial activities
essential oil composition
Editor: Sociedade Brasileira de Química
Rights: aberto
Identifier DOI: 10.1590/S0100-40422009000100015
Address: http://dx.doi.org/10.1590/S0100-40422009000100015
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000100015
Date Issue: 1-Jan-2009
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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