Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/21615
Type: Artigo de periódico
Title: The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
Author: Serrano, Deborah Regina
Zanotti-Magalhães, Eliana Maria
Magalhães, Luiz Augusto
Carvalho, José Ferreira de
Abstract: Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.
Subject: Schistosoma mansoni
Biomphalaria glabrata
hydrocortisone
sporocyst
hemocyte reaction
Editor: Instituto Oswaldo Cruz, Ministério da Saúde
Rights: aberto
Identifier DOI: 10.1590/S0074-02762002000600024
Address: http://dx.doi.org/10.1590/S0074-02762002000600024
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024
Date Issue: 1-Sep-2002
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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