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Type: Artigo de periódico
Title: The stabilizing effects of the acquired immunity on the schistosomiasis transmission modeling - the sensitivity Analysis
Author: Hyun, Mo Yang
Yang, Ariana Campos
Abstract: A mathematical model is proposed to analyze the effects of acquired immunity on the transmission of schistosomiasis in the human host. From this model the prevalence curve dependent on four parameters can be obtained. These parameters were estimated fitting the data by the maximum likelihood method. The model showed a good retrieving capacity of real data from two endemic areas of schistosomiasis: Touros, Brazil (Schistosoma mansoni) and Misungwi, Tanzania (S. haematobium). Also, the average worm burden per person and the dispersion of parasite per person in the community can be obtained from the model. In this paper, the stabilizing effects of the acquired immunity assumption in the model are assessed in terms of the epidemiological variables as follows. Regarded to the prevalence curve, we calculate the confidence interval, and related to the average worm burden and the worm dispersion in the community, the sensitivity analysis (the range of the variation) of both variables with respect to their parameters is performed.
Subject: schistosomiasis
acquired immunity
mathematical model
epidemiological values
sensitivity analysis
Editor: Instituto Oswaldo Cruz, Ministério da Saúde
Rights: aberto
Identifier DOI: 10.1590/S0074-02761998000700009
Date Issue: 1-Jan-1998
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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