Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/21393
Type: Artigo de periódico
Title: Molecular typing of Candida albicans strains isolated from nosocomial candidemia
Title Alternative: Tipificação molecular de espécies de Candida albicans isoladas de candidemia hospitalar
Author: Branchini, Maria Luiza Moretti
Geiger, Débora de Cassia Pires
Fischman, Olga
Pignatari, Antonio Carlos
Abstract: Yeasts of the genus Candida have been recognized as important microorganisms responsible for nosocomial fungemia. Six blood-stream and two intravenous central catheter C. albicans strains were isolated from eight patients and studied by electrophoretic karyotyping of chromosomal DNA by pulsed-field gel electrophoresis. Seven chromosomal DNA profiles were identified. Two patients showed isolates with the same profile, suggesting nosocomial transmission. Karyotyping of C. albicans revealed an excellent discriminatory power among the isolates and may therefore be useful in the study of nosocomial candidemia.
Leveduras do gênero Candida têm sido reconhecidas como importantes causadoras de fungemias hospitalares. Foram estudados os DNA cromossômicos de oito cepas de C. albicans, obtidas de oito pacientes com fungemia hospitalar, por cariotipagem eletroforética através de pulsed-field gel electrophoresis. As cepas foram obtidas pelo isolamento da levedura em seis hemoculturas e duas infecções relacionadas ao uso de cateter intra-venoso central. Foram identificados sete perfis de DNA cromossômico. Dois pacientes mostraram cepas com o mesmo perfil de DNA sugerindo transmissão nosocomial. A cariotipagem eletroforética revelou excelente capacidade discriminatória entre os isolados sendo útil no estudo das candidemias hospitalares.
Subject: Candida albicans
Nosocomial candidemia
Pulsed-field gel electrophoresis
Molecular typing
Editor: Instituto de Medicina Tropical
Rights: aberto
Identifier DOI: 10.1590/S0036-46651995000600002
Address: http://dx.doi.org/10.1590/S0036-46651995000600002
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000600002
Date Issue: 1-Dec-1995
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

Files in This Item:
File Description SizeFormat 
S0036-46651995000600002.pdf915.74 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.