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Type: Artigo de periódico
Title: Gut-central nervous system axis is a target for nutritional therapies
Author: Pimentel, Gustavo D.
Micheletti, Thayana O.
Pace, Fernanda
Rosa, Jose C.
Santos, Ronaldo V. T.
Lira, Fabio S.
Abstract: Historically, in the 1950s, the chemist Linus Pauling established a relationship between decreased longevity and obesity. At this time, with the advent of studies involving the mechanisms that modulate appetite control, some researchers observed that the hypothalamus is the "appetite centre" and that peripheral tissues have important roles in the modulation of gut inflammatory processes and levels of hormones that control food intake. Likewise, the advances of physiological and molecular mechanisms for patients with obesity, type 2 diabetes mellitus, inflammatory bowel diseases, bariatric surgery and anorexia-associated diseases has been greatly appreciated by nutritionists. Therefore, this review highlights the relationship between the gut-central nervous system axis and targets for nutritional therapies.
Subject: Gut
Central nervous system
Inflammatory disease
Editor: Biomed Central Ltd
Rights: fechado
Identifier DOI: 10.1186/1475-2891-11-22
Date Issue: 2012
Appears in Collections:FCM - Artigos e Outros Documentos

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