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Type: Artigo de periódico
Title: Cognitive impairment in antiphospholipid syndrome: evidence from animal models
Author: Appenzeller, Simone
Lapa, Aline Tamires
Guirau, Caio Rodrigues
de Carvalho, Jozelio Freire
Shoenfeld, Yehuda
Abstract: Although antiphospholipid syndrome (APS) is a multisystem prothrombotic condition, its inflammatory nature has been increasingly recognized in recent years. Stroke and transitory ischemic attacks are the neurological manifestations included in APS criteria, however many other neurological involvements have been attributed to antiphospholipid antibodies (aPL), such as seizures, transverse myelitis, and cognitive impairment. In this article we will review evidence from animal model that explain the role of aPL in cognition.
Subject: Animal models
Antiphospholipid syndrome
Cognitive impairment
Editor: Springer
Citation: Clinical Rheumatology. Springer, v.31, n.3, p.403-406, 2012
Rights: fechado
Identifier DOI: 10.1007/s10067-011-1922-z
Date Issue: 2012
Appears in Collections:FCM - Artigos e Outros Documentos

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