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Type: Artigo de periódico
Title: Riboflavina: uma vitamina multifuncional
Title Alternative: Riboflavin: a multifunctional vitamin
Author: Souza, Ana Carolina Santos de
Ferreira, Carmen Veríssima
Jucá, Marilena Bezerra
Aoyama, Hiroshi
Cavagis, Alexandre D. Martins
Peppelenbosch, Maikel P.
Abstract: Riboflavin, a component of the B2 vitaminic complex, plays important roles in biochemistry, especially in redox reactions, due to the ability to participate in both one- and two-electron transfers as well as acting as a photosensitizer. Accordingly, low intakes of this vitamin have been associated with different diseases, including cancer and cardiovascular diseases. Riboflavin is thought to contribute to oxidative stress through its capacity to produce superoxide but, interestingly, it can also promote the reduction of hydroperoxides. This peculiar and multifunctional behavior allows riboflavin to take part in various biochemical pathways as a nucleophile and an electrophile, turning it into a versatile and important biological compound.
Subject: riboflavin
electron transfer
oxidative stress
Editor: Sociedade Brasileira de Química
Citation: Química Nova. Sociedade Brasileira de Química, v. 28, n. 5, p. 887-891, 2005.
Rights: aberto
Identifier DOI: 10.1590/S0100-40422005000500028
Date Issue: 1-Oct-2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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