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Type: Artigo de periódico
Title: Nature-inspired Enzymatic Cascades To Build Valuable Compounds.
Author: Sigrist, Renata
da Costa, Bruna Zucoloto
Marsaioli, Anita Jocelyne
de Oliveira, Luciana Gonzaga
Abstract: Biocatalysis currently is focusing on enzymatic and multi-enzymatic cascade processes instead of single steps imbedded into chemical pathways. Alongside this scientific revolution, this review provides an overview on multi-enzymatic cascades that are responsible for the biosynthesis of some terpenes, alkaloids and polyethers, which are important classes of natural products. Herein, we illustrate the development of studies inspired by multi- and chemo-enzymatic approaches to build the core moieties of polyethers, polypeptide alkaloids, piperidines and pyrrolidines promoted by the joint action of oxidoreductases, hydrolases, cyclases, transaminases and imine reductases.
Subject: Chemo- And Multi-enzymatic Processes
Imine Reductases
Piperidines And Pyrrolidines
Polypeptide Alkaloids
Rights: fechado
Identifier DOI: 10.1016/j.biotechadv.2015.03.010
Date Issue: 2015
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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