Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/202238
Type: Artigo de periódico
Title: Polycystic Ovary Syndrome And Chronic Autoimmune Thyroiditis.
Author: Novais, Jussara de Souza Mayrink
Benetti-Pinto, Cristina Laguna
Garmes, Heraldo Mendes
Jales, Rodrigo Menezes
Juliato, Cássia Raquel Teatin
Abstract: Polycystic ovary syndrome (PCOS) has been associated with an autoimmune origin, either per se or favoring the onset of autoimmune diseases, from a stimulatory action on the inflammatory response. Thus, autoimmune thyroiditis (AIT) could be more prevalent among women with PCOS. To evaluate the prevalence of AIT in women with PCOS. It was a cross-sectional study, in a tertiary center, including 65 women with PCOS and 65 women without this condition. Clinical and laboratory parameters were evaluated and a thyroid ultrasound scan was performed. Levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), anti-thyroid peroxidase (anti-TPO) antibodies, anti-thyroglobulin (anti-TG) antibodies, and thyroid ultrasound findings were evaluated. The prevalence of subclinical hypothyroidism (SCH) in women with PCOS was 16.9% and 6.2% in the non-PCOS group. AIT was more common in the PCOS group compared with the non-PCOS group (43.1% versus 26.2%). But, when it was adjusted by weight and insulin resistance, the difference in the thyroiditis risk was not observed (OR 0.78, CI 0.28-2.16). AIT risk was similar in the PCOS and the non-PCOS group. SCH are more common in women with PCOS, highlighting a need for periodic monitoring of thyroid function.
Subject: Anti-thyroid Peroxidase
Anti-thyroglobulin
Autoimmune Thyroiditis
Polycystic Ovary Syndrome
Subclinical Hypothyroidism
Rights: fechado
Identifier DOI: 10.3109/09513590.2014.958990
Address: http://www.ncbi.nlm.nih.gov/pubmed/25211537
Date Issue: 2015
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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