Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201899
Type: Artigo de periódico
Title: Effect Of Particles Of Ashes Produced From Sugarcane Burning On The Respiratory System Of Rats.
Author: Ferreira, L E N
Muniz, B V
Bittar, T O
Berto, L A
Figueroba, S R
Groppo, F C
Pereira, A C
Abstract: The practice of burning sugarcane obtained by non-mechanized harvesting exposes workers and the people of neighboring towns to high concentrations of particulate matter (PM) that is harmful to health, and may trigger a series of cardiorespiratory diseases. The aim of this study was to analyze the chemical composition of the micro-particles coming from sugarcane burning residues and to verify the effects of this micro-particulate matter on lung and tracheal tissues. Micro-particulate matter (PM10) was obtained by dissolving filter paper containing burnt residues in NaCl solution. This material was instilled into the Wistar rats' nostrils. Histological analyses (hematoxylin and eosin - HE) of cardiac, lung and tracheal tissues were performed. Inflammatory mediators were measured in lung tissues by using ELISA. The chemical composition of the particulate material revealed a large quantity of the phthalic acid ester, high concentrations of phenolic compounds, anthracene and polycyclic aromatic hydrocarbons (PAH). Histological analysis showed a reduction in subjacent conjunctive tissue in the trachea, lung inflammation with inflammatory infiltrate formation and reduction of alveolar spaces and a significant increase (p<0.05) in the release of IL-1α, IL-1β, IL-6, and INF-γ in the group treated with PM10 when compared to the control group. We concluded that the burning sugarcane residues release many particles, which have toxic chemical compounds. The micro-particulate matter can induce alterations in the respiratory system.
Subject: Air Pollutants
Analysis Of Variance
Animals
Chromatography, Gas
Enzyme-linked Immunosorbent Assay
Histological Techniques
Interferon-gamma
Interleukin-1
Interleukin-6
Lung
Particulate Matter
Phenols
Phthalic Acids
Rats
Rats, Wistar
Respiratory System
Saccharum
Trachea
Aromatic Hydrocarbons
Cytokines Release And Lung Inflammation
Particulate Matter
Sugarcane Residues
Trachea Morfology Alterations
Rights: fechado
Identifier DOI: 10.1016/j.envres.2014.07.030
Address: http://www.ncbi.nlm.nih.gov/pubmed/25462680
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_25462680.pdf1.42 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.