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Type: Artigo de periódico
Title: Sinonasal Disorders In Hematopoietic Stem Cell Transplantation.
Author: Bento, Lucas Ricci
Ortiz, Erica
Nicola, Ester Maria Danieli
Vigorito, Afonso C
Sakano, Eulalia
Abstract: hematopoietic stem cell transplantation (HSCT) is associated with more respiratory infections due to immunosuppression. this study aimed to verify the frequency of rhinosinusitis after HSCT, and the association between rhinosinusitis and chronic graft vs. host disease (GVHD) and type of transplantation, clinical treatment, surgical treatment, and survival. this was a retrospective study in a tertiary university hospital. A total of 95 patients with hematological diseases undergoing HSCT between 1996 and 2011 were selected. chronic myeloid leukemia was the most prevalent disease. The type of transplant most often performed was the allogenic type (85.26%). The frequency of rhinosinusitis was 36%, with no difference between the autologous and the allogenic types. Chronic GVHD occurred in 30% of patients. Patients with GVHD had a higher frequency and recurrence of rhinosinusitis, in addition to more frequent need for endoscopic sinusectomy and decreased overall survival. there was a higher frequency of rhinosinusitis in HSCT and GVHD. The type of transplant does not appear to predispose to the occurrence of rhinosinusitis. GVHD seems to be an aggravating factor and requires a more stringent treatment.
Subject: Chronic Disease
Graft Vs Host Disease
Hematologic Diseases
Hematopoietic Stem Cell Transplantation
Retrospective Studies
Condutas Terapêuticas
Doença Enxerto-hospedeiro
Graft Vs. Host Disease
Hematopoietic Stem Cell Transplantation
Therapeutic Conducts
Transplante De Células-tronco Hematopoéticas
Citation: Brazilian Journal Of Otorhinolaryngology. v. 80, n. 4, p. 285-9
Rights: aberto
Identifier DOI: 10.1016/j.bjorl.2014.05.009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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