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Type: Artigo
Title: Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration
Author: Rossato, Franco A.
Zecchin, Karina G.
La Guardia, Paolo G.
Ortega, Rose M.
Alberici, Luciane C.
Costa, Rute A. P.
Catharino, Rodrigo R.
Graner, Edgard
Castilho, Roger F.
Vercesi, Aníbal E.
Abstract: The metabolic enzyme fatty acid synthase (FASN) is responsible for the endogenous synthesis of palmitate, a saturated long-chain fatty acid. In contrast to most normal tissues, a variety of human cancers overexpress FASN. One such cancer is cutaneous mela
Subject: Ácido graxo sintases
Country: Estados Unidos
Editor: Public Library of Science
Citation: Plos One. v. 9, n. 6, p. e101060, 2014.
Rights: Aberto
Identifier DOI: 10.1371/journal.pone.0101060
Date Issue: 2014
Appears in Collections:FCM - Artigos e Outros Documentos
FOP - Artigos e Outros Documentos

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