Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201418
Type: Artigo de periódico
Title: Silk Fibroin And Sodium Alginate Blend: Miscibility And Physical Characteristics.
Author: de Moraes, Mariana Agostini
Silva, Mariana Ferreira
Weska, Raquel Farias
Beppu, Marisa Masumi
Abstract: Films of silk fibroin (SF) and sodium alginate (SA) blends were prepared by solution casting technique. The miscibility of SF and SA in those blends was evaluated and scanning electron microscopy (SEM) revealed that SF/SA 25/75 wt.% blends underwent microscopic phase separation, resulting in globular structures composed mainly of SF. X-ray diffraction indicated the amorphous nature of these blends, even after a treatment with ethanol that turned them insoluble in water. Thermal analyses of blends showed the peaks of degradation of pristine SF and SA shifted to intermediate temperatures. Water vapor permeability, swelling capacity and tensile strength of SF films could be enhanced by blending with SA. Cell viability remained between 90 and 100%, as indicated by in vitro cytotoxicity test. The SF/SA blend with self-assembled SF globules can be used to modulate structural and mechanical properties of the final material and may be used in designing high performance wound dressing.
Subject: Alginates
Animals
Biocompatible Materials
Bombyx
Cho Cells
Cell Survival
Cricetinae
Cricetulus
Fibroins
Glucuronic Acid
Hexuronic Acids
Silk
Temperature
Water
Biomaterials
Biopolymers
Films
Phase Separation
Citation: Materials Science & Engineering. C, Materials For Biological Applications. v. 40, p. 85-91, 2014-Jul.
Rights: fechado
Identifier DOI: 10.1016/j.msec.2014.03.047
Address: http://www.ncbi.nlm.nih.gov/pubmed/24857469
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_24857469.pdf1.18 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.