Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201385
Type: Artigo
Title: Desorption/ionization efficiencies oftriacylglycerols and phospholipidsvia EASI-MS
Author: Fernandes, Anna Maria A. P.
Fernandes, Gabriel D.
Barrera‐Arellano, Daniel
Sá, Gilberto F. de
Lins, Roberto D.
Eberlin, Marcos N.
Alberici, Rosana M.
Abstract: Knowledge of the major effects governing desorption/ionization efficiency is required for the development and application of ambient mass spectrometry. Although all triacylglycerols (TAG) have the same favorable protonation and cationization sites, their desorption/ionization efficiencies can vary dramatically during easy ambient sonic-spray ionization because of structural differences in the carbon chain. To quantify this somewhat surprising and drastic effect, we have performed a systematic investigation of desorption/ionization efficiencies as a function of unsaturation and length for TAG as well as for diacylglycerols, monoacylglycerols and several phospholipids (PL). Affinities for Na(+) as a function of unsaturation level have also been assayed via comprehensive metadynamics calculations to understand the influence of this phenomenon on the ionization efficiency. The results suggest that dipole-dipole interactions within a carbon chain tuned by unsaturation sites govern ionization efficiency of TAG and PL.
Knowledge of the major effects governing desorption/ionization efficiency is required for the development and application ofambient mass spectrometry. Although all triacylglycerols (TAG) have the same favorable protonation and cationization sites,their de
Subject: Lipídeos
Triacilglicerois
Fosfolipídeos
EASI-MS
Simulação de dinâmica molecular
Country: Reino Unido
Editor: John Wiley & Sons
Citation: Journal Of Mass Spectrometry : Jms. v. 49, n. 5, p. 335-41, 2014-May.
Rights: fechado
Fechado
Identifier DOI: 10.1002/jms.3366
Address: https://onlinelibrary.wiley.com/doi/full/10.1002/jms.3366
Date Issue: 2014
Appears in Collections:IQ - Artigos e Outros Documentos
FEA - Artigos e Outros Documentos

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